Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep1252 | Thyroid (non-cancer) | ECE2017

The role of FNDC5 gene expression in irisin level changes accompanying thyroid pathologies

Zybek-Kocik Ariadna , Sawicka-Gutaj Nadia , Andrusiewicz Miroslaw , Waligorska-Stachura Joanna , Bialas Piotr , Skrobisz Jerzy , Ruchala Marek

Irisin is a recently reported, widely discussed new adipo-myokin secreted mainly by muscle tissue. It is a cleaved and secreted part of fibronectin type III domain containing 5, encoded by the FNDC5 gene. Some of the previously published studies claim that alterations of irisin levels in patients affected by thyroid diseases may be connected mainly with accompanying myopathy. However, to date it has not been evaluated, whether the changes in expression of FNDC5</e...